Major Male Health Issues After the Age of 50
After the age of 50, the male body undergoes progressive physiological changes, often gradual and silent, yet highly relevant to overall quality of life.
Among the most common conditions are:
- declining testosterone levels
- reduced physical and mental vitality
- increased fatigue
- changes in erectile function
- reduced male fertility
- urinary symptoms related to prostate health
At this stage of life, prevention, a healthy lifestyle and targeted nutritional support become essential tools and should always be considered alongside medical advice.
Interview with Prof. Ermanno Greco
Prof. Ermanno Greco is one of Italy’s leading experts in reproductive medicine, andrology and couple infertility.
For many years, he has been involved in the prevention, diagnosis and treatment of male and female reproductive conditions, adopting an integrated approach that combines medical therapies, functional nutrition and targeted supplementation.
Professor, why should men over 50 consider targeted supplementation?
Prof. Greco:
“After the age of 50, the efficiency of several metabolic processes decreases. Supplementation is not intended to ‘treat’ diseases, but rather to support specific physiological functions, such as microcirculation, cellular metabolism, hormonal balance and prostate health.”
Let’s start with male vitality and erectile function
Prof. Greco:
“Erectile function is closely linked to vascular health. Amino acids such as arginine and citrulline promote the production of nitric oxide, which is essential for proper vasodilation.”
Male fertility after 50: is it still relevant?
Prof. Greco:
“Absolutely. Age affects semen quality and oxidative stress levels. Antioxidants, vitamin D and selected micronutrients help protect residual reproductive function.”
And what about prostate health?
Prof. Greco:
“With advancing age, benign prostatic hyperplasia becomes increasingly common. Plant-based complexes and antioxidants may contribute to urinary and prostate well-being, especially in mild to moderate cases.”
An Integrated and Personalized Approach
According to Prof. Greco, when properly selected, dietary supplementation can represent a valuable support in male health pathways. The key message is clear: there is no “one-size-fits-all” supplement, but rather different solutions for different needs.
After the age of 50, choices should be personalized based on:
- biological age
- lifestyle
- clinical conditions
- health goals
Always under medical supervision.
Taking care of one’s well-being after 50 means acting consciously through prevention, regular check-ups and appropriate nutritional support. When properly implemented, dietary supplementation can become a valuable long-term ally for male health.


